Rhodococcus equi hyperimmune plasma decreases pneumonia severity after a randomised experimental challenge of neonatal foals

被引:25
|
作者
Sanz, M. G. [1 ]
Loynachan, A. [2 ]
Horohov, D. W. [1 ]
机构
[1] Univ Kentucky, Maxwell H Gluck Equine Res Ctr, Lexington, KY 40546 USA
[2] Univ Kentucky, Dept Vet Sci, Vet Diagnost Lab, Lexington, KY 40546 USA
关键词
SUBCLINICAL PULMONARY ABSCESSES; VIRULENCE; RESPONSES; IGG; PREVENTION; PROTECTION; DIAGNOSIS; ANTIBODY; AGE;
D O I
10.1136/vr.103095
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Since a vaccine is not available against Rhodococcus equi, R equi-specific hyperimmune plasma (HIP) is commonly used, although its efficacy remains controversial. The objective of this study was to evaluate the ability of a commercially available HIP to prevent clinical rhodococcal pneumonia in neonatal foals after experimental challenge.
引用
收藏
页数:7
相关论文
共 27 条
  • [21] Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia
    Angela I. Bordin
    Noah D. Cohen
    Steve Giguère
    Jocelyne M. Bray
    Londa J. Berghaus
    Brenton Scott
    Rena Johnson
    Magnus Hook
    Scientific Reports, 11
  • [22] Association of pneumonia with concentrations of virulent Rhodococcus equi in fecal swabs of foals before and after intrabronchial infection with virulent R. equi
    Cohen, Noah D.
    Kahn, Susanne K.
    Bordin, Angela, I
    Gonzales, Giana M.
    da Silveira, Bibiana Petri
    Bray, Jocelyne M.
    Legere, Rebecca M.
    Ramirez-Cortez, Sophia C.
    JOURNAL OF VETERINARY INTERNAL MEDICINE, 2022, 36 (03) : 1139 - 1145
  • [23] The Effectiveness of Anti-R. equi Hyperimmune Plasma against R. equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R-equi Vaccine
    Erganis, Osman
    Sayin, Zafer
    Hadimli, Hasan Huseyin
    Sakmanoglu, Asli
    Pinarkara, Yasemin
    Ozdemir, Ozgur
    Maden, Mehmet
    SCIENTIFIC WORLD JOURNAL, 2014,
  • [24] Changing policy to treat foals with Rhodococcus equi pneumonia in the later course of disease decreases antimicrobial usage without increasing mortality rate
    Arnold-Lehna, Denise
    Venner, Monica
    Berghaus, Londa J.
    Berghaus, Roy
    Giguere, Steeve
    EQUINE VETERINARY JOURNAL, 2020, 52 (04) : 531 - 537
  • [25] Rhodococcus equi pneumonia in foals: An assessment of the early diagnostic value of serum amyloid A and plasma fibrinogen concentrations in equine clinical practice
    Passamonti, F.
    Vardi, D. M.
    Stefanetti, V.
    Marenzoni, M. L.
    Prato, S.
    Cevese, P.
    Coletti, M.
    Pepe, M.
    Casagrande Proietti, P.
    Olea-Popelka, F.
    VETERINARY JOURNAL, 2015, 203 (02): : 211 - 218
  • [26] Evaluation of white blood cell concentration, plasma fibrinogen concentration, and an agar gel immunodiffusion test for early identification of foals with Rhodococcus equi pneumonia
    Giguère, S
    Hernandez, J
    Gaskin, J
    Miller, C
    Bowman, JL
    JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2003, 222 (06): : 775 - 781
  • [27] Evaluation of white blood cell concentration, plasma fibrinogen concentration, and an agar gel immunodiffusion test for early identification of foals with Rhodococcus equi pneumonia (vol 222, pg 775, 2003)
    Giguere, S
    Hernandez, J
    Gaskin, J
    Miller, C
    Bowman, JL
    JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2003, 223 (09) : 1300 - +