Iron-catalysed allylation-hydrogenation sequences as masked alkyl-alkyl cross-couplings

被引：3

作者：

Bernauer, Josef ^{[1
]}

Wu, Guojiao ^{[1
]}

Jacobi von Wangelin, Axel ^{[1
]}

机构：

[1] Univ Hamburg, Dept Chem, Martin Luther King Pl 6, D-20146 Hamburg, Germany

来源：

RSC ADVANCES | 2019年 / 9卷 / 54期

基金：

欧洲研究理事会;

关键词：

ALKENE HYDROGENATION; GRIGNARD-REAGENTS; COBALT; METAL; TEMPERATURE; SCOPE;

D O I：

10.1039/c9ra07604b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An iron-catalysed allylation of organomagnesium reagents (alkyl, aryl) with simple allyl acetates proceeds under mild conditions (Fe(OAc)(2) or Fe(acac)(2), Et2O, r.t.) to furnish various alkene and styrene derivatives. Mechanistic studies indicate the operation of a homotopic catalyst. The sequential combination of such iron-catalysed allylation with an iron-catalysed hydrogenation results in overall C(sp(3))-C(sp(3))-bond formation that constitutes an attractive alternative to challenging direct cross-coupling protocols with alkyl halides.

引用

页码：31217 / 31223

页数：7

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