A practical approach for regioselective mono-nitration of phenols under mild conditions

被引：3
|
作者：
Chen, Ling-Yan [1 ]
Liu, Tao [1 ]
Zhou, Xiaokun [1 ]
Sun, Zhihua [1 ]
机构：
[1] Shanghai Univ Engn Sci, Coll Chem & Chem Engn, 333 Longteng Rd, Shanghai 201620, Peoples R China
来源：
ARKIVOC | 2014年
关键词：
Nitration; regioselective; metal nitrates; phenolic compounds; HIGHLY EFFICIENT NITRATION; DILUTE NITRIC-ACID; SELECTIVE NITRATION; OXIDATION; OXYGEN; PHASE;
D O I：
10.3998/ark.5550190.p008.587
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cu(NO3)(2)center dot 3H(2)O was demonstrated to be an efficient, regioselective and inexpensive nitrating reagent for the synthesis of mono-nitro substituted phenolic compounds. 12 examples of different phenols were examined. Good yields (67-90%) have been achieved.
引用
收藏
页码：64 / 71
页数：8
相关论文
共 50 条
  • [31] PEG-N2O4:: An efficient nitrating agent for the selective mono- and dinitration of phenols under mild conditions
    Zolfigol, Mohammad Ali
    Madrakian, Elaheh
    Ghaemi, Ezat
    Niknam, Khodabakhsh
    SYNTHETIC COMMUNICATIONS, 2008, 38 (19) : 3366 - 3374
  • [32] An efficient, rapid, and regioselective bromination of anilines and phenols with 1-butyl-3-methylpyridinium tribromide as a new reagent/solvent under mild conditions
    Borikar, Sanjay P.
    Daniel, Thomas
    Paul, Vincent
    TETRAHEDRON LETTERS, 2009, 50 (09) : 1007 - 1009
  • [33] A convenient method for selective mono or dinitration of phenol under mild conditions
    Zolfigol, MA
    Ghaemi, E
    Madrakian, E
    SYNTHETIC COMMUNICATIONS, 2000, 30 (10) : 1689 - 1694
  • [34] Practical allylation with unactivated allylic alcohols under mild conditions
    Li, Shuangshuang
    Qiu, Ju
    Li, Bowen
    Sun, Zuolian
    Xie, Peizhong
    Loh, Teck-Peng
    ORGANIC CHEMISTRY FRONTIERS, 2021, 8 (13) : 3354 - 3359
  • [35] Mild and efficient method for tetrahydropyranylation/depyranylation of alcohols and phenols under neutral conditions
    Reddy, MA
    Reddy, LR
    Bhanumathi, N
    Rao, KR
    SYNTHETIC COMMUNICATIONS, 2000, 30 (23) : 4323 - 4328
  • [36] Efficient Monofluoroalkylation of Thiophenols or Phenols with α-Bromo-α-Fluoroketones under Mild Conditions
    Li, Zhi
    Fang, Mougui
    Wu, Jingjing
    Liu, Yunli
    Liu, Yecheng
    Wu, Fanhong
    SYNTHESIS-STUTTGART, 2021, 53 (13): : 2293 - 2303
  • [37] Regioselective Nitration of N-Alkyl Anilines using tert-Butyl Nitrite under Mild Condition
    Chaudhary, Priyanka
    Gupta, Surabhi
    Muniyappan, Nalluchamy
    Sabiah, Shahulhameed
    Kandasamy, Jeyakumar
    JOURNAL OF ORGANIC CHEMISTRY, 2019, 84 (01): : 104 - 119
  • [38] Regioselective transformation of terminal and internal alkynes into α,α-difluoro ketones under mild conditions
    Lin, Chuyuan
    Lin, Zhenyuan
    Ye, Zhenying
    Chen, Lu
    Li, Yibiao
    Shen, Chengshuo
    Zhang, Min
    TETRAHEDRON LETTERS, 2022, 110
  • [39] Regioselective β-Arylation of α-Angelica Lactone through Isomerization/Addition under Mild Conditions
    Zhuo, Kai-Feng
    Yu, Shang-Hai
    Gong, Tian-Jun
    Fu, Yao
    CHEMSUSCHEM, 2020, 13 (04) : 693 - 697
  • [40] Regioselective mononitration of simple aromatic compounds under mild conditions in ionic liquids
    Smith, K
    Liu, SF
    El-Hiti, GA
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2005, 44 (23) : 8611 - 8615
12345