The XEN of reprogramming

被引：2
|
作者：
Beyret, Ergin [1 ]
Belmonte, Juan Carlos Izpisua [1 ]
机构：
[1] Salk Inst Biol Studies, Gene Express Lab, 10010 N Torrey Pines Rd, La Jolla, CA 92037 USA
来源：
CELL RESEARCH | 2016年 / 26卷 / 02期
关键词：
SMALL-MOLECULE COMPOUNDS; STEM-CELL STATES; SOMATIC-CELLS; PLURIPOTENT STATE;
D O I：
10.1038/cr.2016.9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Reprogramming to pluripotency has thus far required complex procedures involving nuclear transfer, cell fusion or genetic manipulation. Two recent papers from Hongkui Deng's group now show various cell types can be reprogrammed simply by chemicals through an extraembryonic endoderm-like phase instead of the primitive streak-like mesendoderm induced by Yamanaka factors.
引用
收藏
页码：147 / 148
页数：2
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