Expanding evolutionary neuroscience : insights from comparing variation in behavior

被引:41
|
作者
Jourjine, Nicholas [1 ,2 ]
Hoekstra, Hopi E. [1 ,2 ]
机构
[1] Harvard Univ, Dept Mol & Cellular Biol, Dept Organism & Evolutionary Biol, Ctr Brain Sci,Museum Comparat Zool, 16 Divin Ave, Cambridge, MA 02138 USA
[2] Howard Hughes Med Inst, 16 Divin Ave, Cambridge, MA 02138 USA
关键词
GENETIC-BASIS; MOSQUITO PREFERENCE; EGG SIZE; NEURONS; LIFE; CONNECTIVITY; VARIABILITY; RESISTANCE; SPECIATION; POPULATION;
D O I
10.1016/j.neuron.2021.02.002
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Neuroscientists have long studied species with convenient biological features to discover how behavior emerges from conserved molecular, neural, and circuit level processes. With the advent of new tools, from viral vectors and gene editing to automated behavioral analyses, there has been a recent wave of interest in developing new, ?nontraditional?model species. Here, we advocate for a complementary approach to model species development, that is, model clade development, as a way to integrate an evolutionary comparative approach with neurobiological and behavioral experiments. Capitalizing on natural behavioral variation in and investing in experimental tools for model clades will be a valuable strategy for the next generation of neuroscience discovery.
引用
收藏
页码:1084 / 1099
页数:16
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