Cancer;
Pregnancy;
Public health;
Sun;
Vitamin D;
HEART-MUSCLE DISEASE;
NIGHT-SHIFT WORK;
25-HYDROXYVITAMIN D CONCENTRATIONS;
SKIN-CANCER PREVENTION;
MULTIPLE-SCLEROSIS;
D SUPPLEMENTATION;
HYPOVITAMINOSIS-D;
UNITED-KINGDOM;
BREAST-CANCER;
ULTRAVIOLET-B;
D O I:
10.1002/mnfr.200900589
中图分类号:
TS2 [食品工业];
学科分类号:
0832 ;
摘要:
The British Isles have a very cloudy climate and as a result receive fewer hours of clear sunlight than most other industrial regions. The majority of people in these islands have low blood levels of vitamin D [25(OH)D] all year round. Few food products are fortified with vitamin D in the UK and the government does not recommend any vitamin D supplement for most adults in the UK. Diseases associated with vitamin D insufficiency such as cancer, heart disease, diabetes (types 1 and 2) and multiple sclerosis are more frequent in the UK, and particularly in Scotland, than in many other European countries and some, such as multiple sclerosis and diabetes (types 1 and 2), are increasing in incidence. Present knowledge suggests that the risk of some chronic diseases could be reduced if vitamin D intake or sun exposure of the population were increased. Yet policy and public health recommendations of the UK government and its agencies (e.g. the Health Protection Agency, the Food Standards Agency) and of Cancer Research UK have failed to take full account of established and putative benefits of vitamin D and/or sunshine. The epidemic of chronic disease in the UK, which is associated with and caused at least in part by vitamin D insufficiency, has not been adequately recognized by these agencies, and too often measures taken by them have been misguided, inappropriate or ineffective.
机构:
Univ Toronto, Fac Med, Dept Nutr Sci, Toronto, ON, Canada
Univ Toronto, Fac Med, Dept Lab Med & Pathobiol, Toronto, ON, CanadaUniv Toronto, Fac Med, Dept Nutr Sci, Toronto, ON, Canada
机构:
Boston Univ, Med Ctr, Dept Med, Sect Endocrinol Nutr & Diabet,Vitamin D Skin & Bo, Boston, MA 02215 USABoston Univ, Med Ctr, Dept Med, Sect Endocrinol Nutr & Diabet,Vitamin D Skin & Bo, Boston, MA 02215 USA
Holick, Michael F.
BRITISH MEDICAL JOURNAL,
2008,
336
(7657):
: 1318
-
1319
机构:
British Nutr Fdn, High Holborn House,52-54 High Holborn, London WC1V 6RQ, EnglandBritish Nutr Fdn, High Holborn House,52-54 High Holborn, London WC1V 6RQ, England
机构:
Boston Univ, Med Ctr, Dept Med, Sect Endocrinol Diabet & Nutr, Boston, MA 02118 USABoston Univ, Med Ctr, Dept Med, Sect Endocrinol Diabet & Nutr, Boston, MA 02118 USA
Holick, Michael F.
JOURNAL OF CLINICAL AND TRANSLATIONAL ENDOCRINOLOGY,
2014,
1
(04):
: 179
-
186