Immunological role of progesterone in the maintenance of pregnancy

被引：0
|
作者：
Barrera, David [1 ]
Avila, Euclides [1 ]
Diaz, Lorenza [1 ]
机构：
[1] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Reprod Biol, Mexico City 14000, DF, Mexico
来源：
REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION | 2007年 / 59卷 / 02期
关键词：
progesterone; cytokines; NF-kappa B; calcineurin; T-lymphocytes; trophoblast;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Progesterone is an essential hormone for pregnancy maintenance, This hormone acts by binding to its intracellular receptor or by rapid non-genomic actions to regulate a wide variety of biological functions in the feto-placental unit. Progesterone regulates blastocyst implantation and placental development by inducing immunosupression through type Th2 cytokines secretion. This review summarizes current research about the role of progesterone as critical regulator of expression and secretion of cytokines by T-cell and other placental cells.
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页码：139 / 145
页数：7
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