An Efficient, One-Pot, Regioselective Synthesis of 1,4-Diaryl-1H-1,2,3-triazoles Using Click Chemistry

被引：50

作者：

Kumar, Dalip ^{[1
]}

Reddy, Vaddula Buchi ^{[1
]}

机构：

[1] Birla Inst Technol & Sci, Chem Grp, Pilani 333031, Rajasthan, India

来源：

SYNTHESIS-STUTTGART | 2010年 / 10期

关键词：

1,4-diaryl-1H-1,2,3-triazoles; click chemistry; diaryliodonium salts; aryl azides; cycloaddition; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; DIARYLIODONIUM SALTS; 3+2 CYCLOADDITION; TERMINAL ALKYNES; AROMATIC-AMINES; SODIUM-AZIDE; ARYL HALIDES; TRIAZOLE; ACETYLENES; CONVERSION;

D O I：

10.1055/s-0029-1218765

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient, one-pot, regioselective synthesis of 1,4-diaryl-1H-1,2,3-triazoles is described via the copper(I)-catalyzed reaction of diaryliodonium salts, sodium azide and terminal alkynes. The generality of this protocol is demonstrated by the synthesis of a series of 1,4-diaryl-1H-1,2,3-triazoles in good to high yields. The catalyst and reaction solvent are reused without any appreciable reduction in product yield.

引用

页码：1687 / 1691

页数：5

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