Arisandilactone A, a New Triterpenoid from the Fruits of Schisandra arisanensis

被引：27
|
作者：
Cheng, Yuan-Bin [1 ]
Liao, Tzu-Ching [1 ]
Lo, I-Wen [1 ]
Chen, Yu-Chen [1 ]
Kuo, Yuh-Chi [2 ]
Chen, Shun-Ying [3 ]
Chien, Ching-Te [3 ]
Shen, Ya-Ching [1 ]
机构：
[1] Natl Taiwan Univ, Coll Med, Sch Pharm, Taipei 10764, Taiwan
[2] Fu Jen Catholic Univ, Dept Life Sci, Taipei Hsien, Taiwan
[3] Taiwan Forestry Res Inst, Div Silviculture, Taipei, Taiwan
来源：
ORGANIC LETTERS | 2010年 / 12卷 / 05期
关键词：
LIGNANS; CELLS; NORTRITERPENOIDS;
D O I：
10.1021/ol100024r
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A phytochemical investigation of the fruits of Schisandra arisanensis has yielded a novel triterpenoid, arisandilactone A (1). Compound 1 has an unprecedented skeleton having a 5/5/7/5/8/5-fused hexacyclic ring system. The structure of 1 was elucidated by spectroscopic methods, especially 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. A plausible biosynthetic pathway for 1 is also discussed.
引用
收藏
页码：1016 / 1019
页数：4
相关论文
共 50 条
  • [41] Triterpenoid glycosides from fruits of Ecballium elaterium
    Chakravarty, AK
    Sarkar, T
    Das, B
    Masuda, K
    Shiojima, K
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1997, 74 (11-12) : 858 - 863
  • [42] New Cytotoxic Lupane Triterpenes from Perrottetia arisanensis
    Du, Ying-Chi
    Lin, An-Shen
    Wu, Chin-Chung
    Hsieh, Pei-Wen
    Chen, Yung-Husan
    Chen, I-Hsiao
    Chen, Shu-Li
    Yen, Hsin-Fu
    Luebken, Tilo
    Chang, Fang-Rong
    Wu, Yang-Chang
    PLANTA MEDICA, 2009, 75 (08) : 848 - 855
  • [43] Total Synthesis of an Atropisomer of the Schisandra Triterpenoid Schiglautone A
    Ma, Binjie
    Zhao, Yifan
    He, Chi
    Ding, Hanfeng
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (47) : 15567 - 15571
  • [44] Homogeneous ionic liquid microextraction of the active constituents from fruits of Schisandra chinensis and Schisandra sphenanthera
    Xiao, Yao
    Zhang, Hanqi
    ANALYTICA CHIMICA ACTA, 2012, 712 : 78 - 84
  • [45] A NEW COUMARIN GLUCOSIDE FROM DAPHNE-ARISANENSIS
    NIWA, M
    SUGINO, H
    TAKASHIMA, S
    SAKAI, T
    WU, YC
    WU, TS
    KUOH, CS
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1991, 39 (09) : 2422 - 2424
  • [46] A New 27-Norcucurbitane Triterpenoid from the Fruits ofMomordica charantiavar.abbreviata
    Chen, Chiy-Rong
    Liao, Yun-Wen
    Hsu, Jue-Liang
    Lin, Yun-Sheng
    Chang, Chi-, I
    CHEMISTRY OF NATURAL COMPOUNDS, 2020, 56 (04) : 688 - 691
  • [47] 7,8-Secolignans from the fruits of Schisandra neglecta
    Wang, Huan
    Yang, Juan-Xia
    Lou, Jie
    Liu, Gui-You
    Li, Li-Mei
    Sun, Han-Dong
    Xiao, Wei-Lie
    Hu, Qiu-Fen
    Gao, Xue-Mei
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 17 (01) : 27 - 32
  • [48] 24,25-Dihydrolimocinol, a new triterpenoid from fresh fruits of Melia azadirachta
    Misra, Laxminarain
    Gupta, Sonika
    Sangwan, Rajender S.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2015, 92 (01) : 111 - 114
  • [49] Chemical constituents from the fruits of Schisandra sphenanthera and their cytotoxicity activity
    Hee Jae Kwak
    SeonJu Park
    Guijae Yoo
    Jun Hyung Park
    Youngse Oh
    Mira Oh
    Nguyen Xuan Nhiem
    Yun Na Kim
    Eun Ju Jeong
    Seung Hyun Kim
    Revista Brasileira de Farmacognosia, 2019, 29 : 578 - 581
  • [50] Chemical constituents from the fruits of Schisandra sphenanthera and their cytotoxicity activity
    Kwak, Hee Jae
    Park, SeonJu
    Yoo, Guijae
    Park, Jun Hyung
    Oh, Youngse
    Oh, Mira
    Nhiem, Nguyen Xuan
    Kim, Yun Na
    Jeong, Eun Ju
    Kim, Seung Hyun
    REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2019, 29 (05): : 578 - 581
12345