Arisandilactone A, a New Triterpenoid from the Fruits of Schisandra arisanensis

被引：27
|
作者：
Cheng, Yuan-Bin [1 ]
Liao, Tzu-Ching [1 ]
Lo, I-Wen [1 ]
Chen, Yu-Chen [1 ]
Kuo, Yuh-Chi [2 ]
Chen, Shun-Ying [3 ]
Chien, Ching-Te [3 ]
Shen, Ya-Ching [1 ]
机构：
[1] Natl Taiwan Univ, Coll Med, Sch Pharm, Taipei 10764, Taiwan
[2] Fu Jen Catholic Univ, Dept Life Sci, Taipei Hsien, Taiwan
[3] Taiwan Forestry Res Inst, Div Silviculture, Taipei, Taiwan
来源：
ORGANIC LETTERS | 2010年 / 12卷 / 05期
关键词：
LIGNANS; CELLS; NORTRITERPENOIDS;
D O I：
10.1021/ol100024r
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A phytochemical investigation of the fruits of Schisandra arisanensis has yielded a novel triterpenoid, arisandilactone A (1). Compound 1 has an unprecedented skeleton having a 5/5/7/5/8/5-fused hexacyclic ring system. The structure of 1 was elucidated by spectroscopic methods, especially 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. A plausible biosynthetic pathway for 1 is also discussed.
引用
收藏
页码：1016 / 1019
页数：4
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