Accuracy of prostate volume measurements in vitro using three-dimensional ultrasound

Rationale and Objectives. We assessed the ability of a three-dimensional (3D) Methods. Multiple two-dimensional ultrasound images of cadaver prostates scanned in a water bath were reconstructed into three-dimensional (3D) images. The volumes of the prostates were calculated from these 3D images and compared with the actual volumes. Multiple 3D ultrasound volume readings were evaluated for precision. Results. The slope of the best-fit line correlating 3D ultrasound estimated volume and true volume was 1.006 +/- 0.007. The average error was 0.36 +/- 1.17 cm(3); the coefficient of determination (r(2)), which is the measure of the straight-line relationship, was .9997; and the standard error was 1.15 cm(3). Conclusion. Three-dimensional ultrasound images accurately reflect true prostate volumes measured in vitro.