intervention time series analysis;
pertussis vaccination;
whooping-cough epidemics;
D O I:
10.1016/S0168-8510(00)00096-8
中图分类号:
R19 [保健组织与事业(卫生事业管理)];
学科分类号:
摘要:
We use the ARIMA model with intervention in order to analyse the epidemiological situation of whooping-cough in England and Wales for the period of 1940-1990. The ARIMA modelling of this illness contains intervention variables, such as the introduction of widespread vaccination in 1957 and the fail in the level of vaccination down to 30% in 1978. The results of this analysis confirm the role of the intervention variables on the evolution of the morbidity due to whooping-cough, by quantifying their impact on the level of the morbidity, as well as the delay needed before they have an influence on the increase of recorded cases of whooping-cough. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved. JEL classification: C22: I12.