Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems

被引：60
|
作者：
Rethore, G.
Montier, T.
Le Gall, T.
Delepine, P.
Cammas-Marion, S.
Lemiegre, L.
Lehn, P.
Benvegnu, T.
机构：
[1] Ecole Natl Super Chim Rennes, CNRS, UMR Sci Chim Rennes 6226, Equipe Synth Organ & Syst Organ, F-35700 Rennes, France
[2] Univ Bretagne Occidentale, Fac Med & Sci Sante, INSERM,U613, Inst Synergie Sci & Sante, F-29220 Brest, France
来源：
CHEMICAL COMMUNICATIONS | 2007年 / 20期
关键词：
D O I：
10.1039/b618568a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Novel cationic liposomes, termed "archaeosomes", based on mixtures of neutral/cationic bilayer-forming lipids and archaeobacterial synthetic tetraether-type bipolar lipids show efficient in vitro gene transfection properties and represent a new approach for modulating the lipidic membrane fluidity of the complexes they form with DNA.
引用
收藏
页码：2054 / 2056
页数：3
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