Deficiency of B Crystallin Augments ER Stress-Induced Apoptosis by Accentuating Mitochondrial Dysfunction in RPE Cells

被引:0
|
作者
Dou, G. [1 ]
Sreekumar, P. G. [1 ]
Spee, C. [1 ]
He, S. [1 ]
Ryan, S. J. [1 ]
Kannan, R. [1 ]
Hinton, D. R. [1 ,2 ]
机构
[1] Univ Southern Calif, Doheny Eye Inst, Ophthalmol, Los Angeles, CA USA
[2] Univ Southern Calif, Keck Sch Med, Pathol, Los Angeles, CA 90033 USA
关键词
stress response; retinal pigment epithelium; mitochondria;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
1438
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein
    Ching-Chi Chiu
    Yi-Hsin Weng
    Tu-Hsueh Yeh
    Juu-Chin Lu
    Wan-Shia Chen
    Allen Han-Ren Li
    Ying-Ling Chen
    Kuo-Chen Wei
    Hung-Li Wang
    Molecular Neurobiology, 2023, 60 : 2706 - 2728
  • [42] CaMKII is a central mediator of ER stress-induced macrophage apoptosis
    Timmins, Jenelle M.
    Seimon, Tracie A.
    Lim, Wahseng
    Li, Gang
    Tabas, Ira
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2008, 28 (06) : E43 - E43
  • [43] αNAC depletion as an initiator of ER stress-induced apoptosis in hypoxia
    Hotokezaka, Y.
    van Leyen, K.
    Lo, E. H.
    Beatrix, B.
    Katayama, I.
    Jin, G.
    Nakamura, T.
    CELL DEATH AND DIFFERENTIATION, 2009, 16 (11): : 1505 - 1514
  • [44] Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein
    Chiu, Ching-Chi
    Weng, Yi-Hsin
    Yeh, Tu-Hsueh
    Lu, Juu-Chin
    Chen, Wan-Shia
    Li, Allen Han-Ren
    Chen, Ying-Ling
    Wei, Kuo-Chen
    Wang, Hung-Li
    MOLECULAR NEUROBIOLOGY, 2023, 60 (05) : 2706 - 2728
  • [45] Alpha B-Crystallin Overexpression Protects Oligodendrocyte Precursor Cells Against Oxidative Stress-Induced Apoptosis Through the Akt Pathway
    Ji Young Kim
    Chan Hyung Kim
    Eun Young Lee
    Je Hoon Seo
    Journal of Molecular Neuroscience, 2020, 70 : 751 - 758
  • [46] Alpha B-Crystallin Overexpression Protects Oligodendrocyte Precursor Cells Against Oxidative Stress-Induced Apoptosis Through the Akt Pathway
    Kim, Ji Young
    Kim, Chan Hyung
    Lee, Eun Young
    Seo, Je Hoon
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2020, 70 (05) : 751 - 758
  • [47] CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells
    Kim, Wootae
    Jeong, Joo-Won
    Kim, Ja-Eun
    TUMOR BIOLOGY, 2014, 35 (11) : 10919 - 10929
  • [48] αNAC depletion as an initiator of ER stress-induced apoptosis in hypoxia
    Y Hotokezaka
    K van Leyen
    E H Lo
    B Beatrix
    I Katayama
    G Jin
    T Nakamura
    Cell Death & Differentiation, 2009, 16 : 1505 - 1514
  • [49] The selenoprotein SeIS is induced by endoplasmic reticulum stress and is involved in protecting cells from ER stress-induced cytotoxicity and apoptosis
    Kim, KH
    Skelton, J
    Walder, K
    Yuan, G
    Collier, G
    Kissebah, A
    OBESITY RESEARCH, 2005, 13 : A41 - A41
  • [50] αB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation
    Shin, Joo-Hyun
    Kim, Seung-Woo
    Lim, Chae-Moon
    Jeong, Ji-Young
    Piao, Chun-Shu
    Lee, Ja-Kyeong
    NEUROSCIENCE RESEARCH, 2009, 64 (04) : 355 - 361