An aryl to imidoyl palladium migration process involving intramolecular C-H activation

被引：167

作者：

Zhao, Jian ^{[1
]}

Yue, Dawei ^{[1
]}

Campo, Marino A. ^{[1
]}

Larock, Richard C. ^{[1
]}

机构：

[1] Iowa State Univ Sci & Technol, Dept Chem, Ames, IA 50011 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 16期

关键词：

D O I：

10.1021/ja070657l

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biologically interesting fluoren-9-one and xanthen-9-one derivatives have been prepared by a novel aryl to imidoyl palladium migration, followed by intramolecular arylation. The fluoren-9-one synthesis appears to involve both a palladium migration mechanism and a C-H activation process proceeding through an unprecedented organopalladium(IV) hydride intermediate. The results from deuterium labeling experiments are consistent with the proposed dual mechanism.

引用

页码：5288 / 5295

页数：8

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