Allele and haplotype frequencies of HLA-A, -B, -C,-DRB1,-DQB1 in Northern Ossetians from Vladikavkaz, Russia

被引：0
|
作者：
Kuzminova, Elena [1 ]
Khamaganova, Ekaterina [1 ]
Gaponova, Tatiana [1 ]
Savchenko, Valeriy [1 ]
机构：
[1] Res Ctr Hematol, Novy Zykovsky Proezd 4, Moscow 125167, Russia
来源：
HUMAN IMMUNOLOGY | 2018年 / 79卷 / 10期
关键词：
D O I：
10.1016/j.humimm.2018.07.231
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This report shows the HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies in a population of 127 healthy Ossetian donors of blood marrow from Vladikavkaz, Russia. First- and second-field (for HLA-C locus) HLA genotyping was performed by polymerase chain reaction sequence-specific priming and/or oligonucleotide probes. Statistical analysis were performed using gene counting and Arlequin software packages. There was no deviation from Hardy-Weinberg equilibrium for all tested loci. The HLA genotypic and haplotypic data of the Ossetians reported here are available in free access at the Allele Frequencies Net Database (http://www.allelefrequencies.net). This data can serve as a reference database for further HLA-based studies in population genetics.
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页码：709 / 710
页数：2
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