Conjugate addition of amino acid side chains to alkynones and alkynoic acid derivatives

被引：33

作者：

Crisp, GT ^{[1
]}

Millan, MJ ^{[1
]}

机构：

[1] Univ Adelaide, Dept Chem, Adelaide, SA 5005, Australia

来源：

TETRAHEDRON | 1998年 / 54卷 / 3-4期

关键词：

D O I：

10.1016/S0040-4020(97)10323-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Suitably protected amino acids were used to investigate the Michael addition of the sulfanyl group of cysteine, the hydroxyl group of serine and the epsilon-amino group of lysine to a conjugated alkynone, alkynoic ester and alkynoic amide. The expected heterosubstituted vinyl product was formed in each case. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：637 / 648

页数：12

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