Evolving therapeutic goals in Crohn's disease management

被引：12

作者：

Chateau, Thomas ^{[1
,2
,3
]}

Peyrin-Biroulet, Laurent ^{[2
,3
]}

机构：

[1] Univ Grenoble Alpes, Univ Hosp Grenoble, Dept Hepatogastroenterol, Grenoble, France

[2] Univ Lorraine, Dept Gastroenterol, Univ Hosp Nancy, Vandoeuvre Les Nancy, France

[3] Univ Lorraine, Inserm NGERE, Univ Hosp Nancy, Vandoeuvre Les Nancy, France

来源：

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL | 2020年 / 8卷 / 02期

关键词：

Tight control; Crohn's disease; treat-to-target; INFLAMMATORY-BOWEL-DISEASE; C-REACTIVE PROTEIN; FECAL CALPROTECTIN; ENDOSCOPIC ACTIVITY; CLINICAL RELAPSE; DEEP REMISSION; ACTIVITY INDEX; INFLIXIMAB; AZATHIOPRINE; MULTICENTER;

D O I：

10.1177/2050640619887316

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The main objectives in Crohn's disease are to avoid disease complications and preserve the patient's quality of life. Early disease control and close monitoring with specific targets to reach might be the only way to change the disease course. In two decades, we have moved from clinical response to full remission (clinical and endoscopic remission) requiring a tight monitoring of both symptoms and objective signs of inflammation. This review summarizes the concepts of tight control and treat-to-target and their potential for disease modification.

引用

页码：133 / 139

页数：7

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