Immunoglobulins and physiopathology: from current indications to potential indications

被引:0
|
作者
Mouthon, L. [1 ]
Guilpain, P. [1 ]
机构
[1] Hop Cochin, APHP, Serv Med Interne, Ctr Reference Vasc Necrosantes & Sclerodermie Sys, F-75679 Paris 14, France
来源
REVUE DE MEDECINE INTERNE | 2007年 / 28卷
关键词
intravenous immunoglobulin; IgG; autoimmune disease;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Intravenous Immunoglobulin (IVIg) are therapeutic preparations of normal human IgG that are obtained from pools of plama from healthy blood donors. IVIg can be used at high dose as an immunomodulatory agent in a large number of autoimmune and/or systemic inflammatory diseases, particularly in hematologic or neurologic diseases. Mechanisms of action of IVIg are multiple and intricated. The development of new therapeutic trials in association with analyses of mechanisms of action should help to define new indications of IVIg therapy. (C) 2007 Elsevier Masson SAS. Tous droits reserves.
引用
收藏
页码:11 / 17
页数:7
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