Candidemia in the Intensive Care Unit

被引：40

作者：

Epelbaum, Oleg ^{[1
]}

Chasan, Rachel ^{[2
]}

机构：

[1] New York Med Coll, Westchester Med Ctr, Div Pulm Crit Care & Sleep Med, 100 Woods Rd,Macy Pavil Room 1042, Valhalla, NY 10595 USA

[2] Icahn Sch Med Mt Sinai, Div Infect Dis, One Gustave L Levy Pl,Box 1090, New York, NY 10029 USA

来源：

CLINICS IN CHEST MEDICINE | 2017年 / 38卷 / 03期

关键词：

Candidemia; Invasive candidiasis; Candida; Intensive care unit; Critical care; Fungal infection; CRITICALLY-ILL PATIENTS; BLOOD-STREAM INFECTIONS; PLACEBO-CONTROLLED TRIAL; LIPOSOMAL AMPHOTERICIN-B; INVASIVE CANDIDIASIS; RISK-FACTORS; ANTIFUNGAL THERAPY; NOSOCOMIAL CANDIDEMIA; DOUBLE-BLIND; ATTRIBUTABLE MORTALITY;

D O I：

10.1016/j.ccm.2017.04.010

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Candidemia presents several challenge's to the intensive care unit (ICU) community. Recognition and treatment of this infection is frequently delayed, with dramatic clinical deterioration and death often preceding the detection of Candida in blood cultures. Identification of individual patients at the highest risk for developing candidemia remains an imperfect science; the role of antifungal therapy before culture diagnosis is yet to be fully defined in the ICU. The absence of well-established molecular techniques for early detection of candidemia hinders efforts to reduce the heavy clinical and economic impact of this infection. Echinocandins are the recommended antifungal drug class for the treatment of ICU candidemia.

引用

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页码：493 / +

页数：18

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