Review: Placental adaptations to the presence of maternal asthma during pregnancy

被引：31
|
作者：
Meakin, A. S. [1 ]
Saif, Z. [1 ]
Jones, A. R. [1 ]
Aviles, P. F. Valenzula [1 ]
Clifton, V. L. [1 ]
机构：
[1] Univ Queensland, Mater Med Res Inst, Brisbane, Qld, Australia
来源：
PLACENTA | 2017年 / 54卷
关键词：
Placenta; Asthma; Fetus; Sex; Growth; GLUCOCORTICOID-RECEPTOR ISOFORMS; ANTIOXIDANT ENZYME-ACTIVITY; GENE-EXPRESSION; FETAL SEX; BIOLOGICAL OXIDATION; PERINATAL OUTCOMES; GROWTH RESTRICTION; CANCER CELLS; CORTISOL; TESTOSTERONE;
D O I：
10.1016/j.placenta.2017.01.123
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Asthma is a highly prevalent chronic medical condition affecting an estimated 12% of pregnant, women each year, with prevalence of asthma greatest (up to 16%) among the socially disadvantaged. Maternal asthma is associated with significant perinatal morbidity and mortality including preterm births, neonatal hospitalisations and low birthweight outcomes each year. We have identified that the placenta adapts to the presence of chronic, maternal asthma during pregnancy in a sex specific manner that may confer sex differences in fetal outcome. The male fetus was at greater risk of a poor outcome than a female fetus in the presence of maternal asthma and an acute inflammatory event such as an asthma exacerbation. This review will examine the role of sex specific differences in placental function on fetal growth and survival. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：17 / 23
页数：7
相关论文
共 50 条
  • [1] The presence of maternal asthma during pregnancy suppresses the placental pro-inflammatory response to an immune challenge in vitro
    Scott, N. M.
    Hodyl, N. A.
    Osei-Kumah, A.
    Stark, M. J.
    Smith, R.
    Clifton, V. L.
    PLACENTA, 2011, 32 (06) : 454 - 461
  • [2] Maternal Hematologic Neoplasms during Pregnancy: Review of Placental Findings
    Rubrecht, Ashlie
    Seifert, Robert
    Shenoy, Archana
    MODERN PATHOLOGY, 2020, 33 (SUPPL 2) : 1745 - 1746
  • [3] Maternal Hematologic Neoplasms during Pregnancy: Review of Placental Findings
    Rubrecht, Ashlie
    Seifert, Robert
    Shenoy, Archana
    LABORATORY INVESTIGATION, 2020, 100 (SUPPL 1) : 1745 - 1746
  • [4] Maternal β-Cell Adaptations in Pregnancy and Placental Signalling: Implications for Gestational Diabetes
    Moyce, Brittany L.
    Dolinsky, Vernon W.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (11)
  • [5] The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation
    Napso, Tina
    Yong, Hannah E. J.
    Lopez-Tello, Jorge
    Sferruzzi-Perri, Amanda N.
    FRONTIERS IN PHYSIOLOGY, 2018, 9
  • [6] Maternal asthma during pregnancy and risks of allergy and asthma in progeny: a systematic review protocol
    Roff, Andrea J.
    Morrison, Janna L.
    Tai, Andrew
    Clifton, Vicki L.
    Gatford, Kathryn L.
    JBI EVIDENCE SYNTHESIS, 2021, 19 (08) : 2007 - 2013
  • [7] The impact of maternal asthma during pregnancy on fetal growth and development: a review
    Meakin, Ashley S.
    Saif, Zarqa
    Seedat, Nabila
    Clifton, Vicki L.
    EXPERT REVIEW OF RESPIRATORY MEDICINE, 2020, 14 (12) : 1207 - 1216
  • [8] Sexually dimorphic effects of maternal asthma during pregnancy on placental glucocorticoid metabolism and fetal growth
    Vicki L. Clifton
    Cell and Tissue Research, 2005, 322 : 63 - 71
  • [9] Sexually dimorphic effects of maternal asthma during pregnancy on placental glucocorticoid metabolism and fetal growth
    Clifton, VL
    CELL AND TISSUE RESEARCH, 2005, 322 (01) : 63 - 71
  • [10] Metabolic Adaptations of the Maternal Heart During Pregnancy and Postpartum
    Collins, Helen E.
    Fulghum, Kyle
    McNally, Lindsey
    Foster, Mallory Z.
    Brittian, Kenneth
    Chariker, Julia
    Uchida, Shizuka
    Lorkiewicz, Pawel
    Jones, Steven P.
    Hill, Bradford G.
    CIRCULATION, 2021, 144
12345