AN IN VIVO MODEL TO ASSESS BRAIN mGLUR2 TARGET ENGAGEMENT: CHARACTERISATION OF ORTHOSTERIC AND NON COMPETITIVE mGLUR2/3 ANTAGONISTS

被引:0
|
作者
Girard, Francoise [1 ]
Campo, Brice [1 ]
Celanire, Sylvain [1 ]
Lasserre, Sandrine [1 ]
Rizzo, Olivier [1 ]
Bessif, Abdelhak [1 ]
Royer-Urios, Isabelle [1 ]
Poli, Sonia [1 ]
Le Poul, Emmanuel [1 ]
机构
[1] Addex Pharmaceut SA, CH-1228 Plan Les Ouates, Switzerland
关键词
METABOTROPIC GLUTAMATE RECEPTORS; POTENT;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:95 / 95
页数:1
相关论文
共 50 条
  • [31] Characterization of an mGluR2/3 Negative Allosteric Modulator in Rodent Models of Depression
    Campo, Brice
    Kalinichev, Mikhail
    Lambeng, Nathalie
    El Yacoubi, M.
    Royer-Urios, Isabelle
    Schneider, Manfred
    Legrand, Coline
    Parron, Delphine
    Girard, Francoise
    Bessif, Abdelhak
    Poli, Sonia
    Vaugeois, Jean-Marie
    Le Poul, Emmanuel
    Celanire, Sylvain
    JOURNAL OF NEUROGENETICS, 2011, 25 (04) : 152 - 166
  • [32] Positive and negative modulation of circadian activity rhythms by mGluR5 and mGluR2/3 metabotropic glutamate receptors
    Gannon, Robert L.
    Millan, Mark J.
    NEUROPHARMACOLOGY, 2011, 60 (2-3) : 209 - 215
  • [33] Effects of mGluR2 Blockade on Operant Delayed Non-Matching to Position in Rats
    Steckler, T.
    Aerts, N.
    Donck, L. Ver
    Talpos, J.
    CURRENT NEUROPHARMACOLOGY, 2014, 12 : 58 - 58
  • [34] Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus
    Blumcke, I
    Behle, K
    Malitschek, B
    Kuhn, R
    Knopfel, T
    Wolf, HK
    Wiestler, OD
    BRAIN RESEARCH, 1996, 736 (1-2) : 217 - 226
  • [35] RESTORED SENSITIVITY TO THE INTEROCEPTIVE EFFECTS OF ALCOHOL FOLLOWING CHRONIC CORTICOSTERONE: INVOLVEMENT OF MGLUR5 AND MGLUR2/3
    Besheer, J.
    Jaramillo, A. A.
    Frisbee, S.
    Fisher, K. R.
    Whang, A.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2014, 38 : 17A - 17A
  • [36] METABOTROPIC GLUTAMATE RECEPTOR-MEDIATED PRESYNAPTIC DEPRESSION AT CORTICOSTRIATAL SYNAPSES INVOLVES MGLUR2 OR MGLUR3
    LOVINGER, DM
    MCCOOL, BA
    JOURNAL OF NEUROPHYSIOLOGY, 1995, 73 (03) : 1076 - 1083
  • [37] Immunocytochemical pattern of the group II mGluR2/3 and the group III mGluR4a in the rat adrenal medulla
    Sarría, R
    Mateos, JM
    Losada, J
    Benítez, R
    Osorio, A
    Elezparai, I
    Azkue, J
    Kuhn, R
    Grandes, P
    NEUROPHARMACOLOGY, 1999, 38 (10) : A39 - A39
  • [38] Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression
    Wood, Christian M.
    Wafford, Keith A.
    McCarthy, Andrew P.
    Hewes, Nicola
    Shanks, Elaine
    Lodge, David
    Robinson, Emma S. J.
    NEUROPHARMACOLOGY, 2018, 140 : 246 - 259
  • [39] Role of mGluR2/3 in the behavioral-stimulant effects of cocaine in squirrel monkeys
    Bauzo, Rayna M.
    Zhou, Mi
    Kimmel, Heather L.
    Howell, Leonard L.
    FASEB JOURNAL, 2007, 21 (06): : A777 - A778
  • [40] MOLECULAR DYNAMICS SIMULATION OF THE mGLUR2/mGLUR3-5HT2A DIMERS IN AN EXPLICIT DMPC-LIPID BILAYER
    Costantino, Gabriele
    Bruno, Agostino
    Entrena Guadix, Antonio
    DRUGS OF THE FUTURE, 2009, 34 : 104 - 104