AN IN VIVO MODEL TO ASSESS BRAIN mGLUR2 TARGET ENGAGEMENT: CHARACTERISATION OF ORTHOSTERIC AND NON COMPETITIVE mGLUR2/3 ANTAGONISTS

被引:0
|
作者
Girard, Francoise [1 ]
Campo, Brice [1 ]
Celanire, Sylvain [1 ]
Lasserre, Sandrine [1 ]
Rizzo, Olivier [1 ]
Bessif, Abdelhak [1 ]
Royer-Urios, Isabelle [1 ]
Poli, Sonia [1 ]
Le Poul, Emmanuel [1 ]
机构
[1] Addex Pharmaceut SA, CH-1228 Plan Les Ouates, Switzerland
关键词
METABOTROPIC GLUTAMATE RECEPTORS; POTENT;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:95 / 95
页数:1
相关论文
共 50 条
  • [1] mGluR2 immunolocalisation in the human brain
    Phillips, T
    Rees, S
    Emson, P
    EUROPEAN JOURNAL OF NEUROSCIENCE, 1998, 10 : 289 - 289
  • [2] Effect of mGluR2 and mGluR2/3 activators on parkinsonism in the MPTP-lesioned non-human primate
    Frouni, Imane
    Kwan, Cynthia
    Bedard, Dominique
    Hamadjida, Adjia
    Kang, Woojin
    Belliveau, Sebastien
    Nuara, Stephen G.
    Gourdon, Jim C.
    Huot, Philippe
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2024, 397 (11) : 9135 - 9147
  • [3] Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495
    Linden, A. -M.
    Johnson, B. G.
    Trokovic, Nina
    Korpi, E. R.
    Schoepp, D. D.
    NEUROPHARMACOLOGY, 2009, 57 (02) : 172 - 182
  • [4] A SELECTIVE MGLUR2 POSITIVE ALLOSTERIC MODULATOR RADIOLIGAND DEFINES THE MGLUR2 DISTRIBUTION IN RAT, RHESUS AND HUMAN BRAIN
    Jacobson, Marlene
    Pascarella, D. M.
    Brnardic, E. J.
    Hartingh, T. J.
    O'Brien, J. A.
    Magliaro, B. C.
    Zeng, Z.
    Garbaccio, R. M.
    Converso, A.
    Tang, Y. S.
    Fraley, M. E.
    Hutson, P. H.
    SCHIZOPHRENIA BULLETIN, 2009, 35 : 336 - 336
  • [5] Promise of mGluR2/3 activators in psychiatry
    Conn, P. Jeffrey
    Jones, Carrie K.
    NEUROPSYCHOPHARMACOLOGY, 2009, 34 (01) : 248 - 249
  • [6] Promise of mGluR2/3 activators in psychiatry
    P Jeffrey Conn
    Carrie K Jones
    Neuropsychopharmacology, 2009, 34 : 248 - 249
  • [7] mGluR2/3 in the Lateral Amygdala is Required for Fear Extinction: Cortical Input Synapses onto the Lateral Amygdala as a Target Site of the mGluR2/3 Action
    Kim, Jihye
    An, Bobae
    Kim, Jeongyeon
    Park, Sewon
    Park, Sungmo
    Hong, Ingie
    Lee, Sukwon
    Park, Kyungjoon
    Choi, Sukwoo
    NEUROPSYCHOPHARMACOLOGY, 2015, 40 (13) : 2916 - 2928
  • [8] mGluR2/3 in the Lateral Amygdala is Required for Fear Extinction: Cortical Input Synapses onto the Lateral Amygdala as a Target Site of the mGluR2/3 Action
    Jihye Kim
    Bobae An
    Jeongyeon Kim
    Sewon Park
    Sungmo Park
    Ingie Hong
    Sukwon Lee
    Kyungjoon Park
    Sukwoo Choi
    Neuropsychopharmacology, 2015, 40 : 2916 - 2928
  • [9] Metabotropic glutamate receptors and transmitter output: in vivo studies with new potent mGluR1 and mGluR2 antagonists
    Moroni, F
    Cozzi, A
    Lombardi, G
    Leonardi, P
    Carfi, M
    Attucci, S
    Peruginelli, F
    Pellicciari, R
    METABOTROPIC GLUTAMATE RECEPTORS AND BRAIN FUNCTION, 1998, 12 : 225 - 234
  • [10] Regulation of mGluR2/3 by cystine glutamate exchange
    Kalivas, P
    Moran, M
    Seamans, J
    NEUROPHARMACOLOGY, 2005, 49 : 251 - 251