The role of complement and natural antibody in intestinal ischemia-reperfusion injury

被引：1
|
作者：
Austen, WG
Kobzik, L
Carroll, MC
Hechtman, HB
Moore, FD
机构：
[1] Brigham & Womens Hosp, Boston, MA 02215 USA
[2] Harvard Univ, Sch Med, Dept Surg & Pathol, Boston, MA USA
来源：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2003年 / 16卷 / 01期
关键词：
complement; antibody; ischemia; reperfusion;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Activation of the complement cascade is central to many types of injury. Ischemia-reperfusion is an important example of such an event. Using intestinal ischemia-reperfusion as a model, we have further elucidated the importance and mechanism of this activation. Of novel is the evidence that natural antibody is a trigger for these events via recognition of self-antigen. In this article, we review the role of natural antibody and complement in intestinal ischemia-reperfusion injury. It is hoped that this study will ultimately lead to better understanding of these important modulators and their role in this type of injury.
引用
收藏
页码：1 / 8
页数：8
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