Experimental and computational analysis of droplet formation in a high-performance flow-focusing geometry

被引:50
|
作者
Ong, Wee-Liat
Hua, Jinsong
Zhang, Baili
Teo, Teng-Yuan
Zhuo, Junlong
Nguyen, Nam-Trung
Ranganathan, Nagarajan
Yobas, Levent
机构
[1] Inst Microelect, BioMicrofluid Grp, Singapore 117685, Singapore
[2] Inst High Performance Comp, Singapore 117528, Singapore
[3] Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore
[4] Nanyang Technol Univ, Sch Mech & Aerosp Engn, Singapore 639798, Singapore
关键词
droplet; digital microfluidics; emulsion; flow-focusing; circular constriction; two-phase flow; simulation;
D O I
10.1016/j.sna.2007.04.053
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Detailed experimental and simulation studies are performed and presented to further substantiate the previously reported high-performance flow-focusing geometry for droplet generation. In this geometry, water-in-oil droplets are formed through a three-dimensional (3D) circular orifice directly integrated inside a silicon microchannel. The geometry ensures controlled breakup of droplets for a wide range of flow rates. Simulations are provided using computational fluid dynamics software to elucidate the flow behavior nearby the 3D circular orifice. In addition, experimental results on the droplet generation characteristics are obtained both from the 3D circular constriction as well as quasi-2D (213) rectangular constriction that are typically used in flow-focusing devices. Direct comparison of these results further supports the claim that droplets formed by the 3D circular orifice show noticeably increased sensitivity against the flow rate of the continuous oil-phase both in droplet size and generation frequency. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:203 / 212
页数:10
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