CLINICAL TRIALS FOR EARLY (PRE-DEMENTIA) ALZHEIMER'S DISEASE: A CASE FOR MILD COGNITIVE IMPAIRMENT

被引：0

作者：

Petersen, R. C. ^{[1
]}

机构：

[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA

来源：

JOURNAL OF NUTRITION HEALTH & AGING | 2010年 / 14卷 / 04期

关键词：

COMMUNITY;

D O I：

暂无

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

A goal of many clinical trials for Alzheimer's disease is to develop disease-modifying therapies for the pre-dementia period of the Alzheimer's disease process. However, there are no clinical criteria for characterizing subjects in this range. The construct of amnestic mild cognitive impairment has been extensively investigated and may provide useful clinical criteria for this clinical stage. It is proposed that the clinical criteria for mild cognitive impairment be enriched with imaging and other biomarkers to improve the specificity of the outcome, and these criteria might suffice for pre-dementia clinical trials.

引用

页码：304 / 305

页数：2

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