Common variants in the GLP-1 receptor are associated with glycaemic response to GLP-1 receptor agonists in observational and large RCT data: an IMI-DIRECT study

被引：0
|
作者：
Dawed, A. Y. [1 ]
Mari, A. [2 ]
McDonald, T. J. [3 ,4 ]
Robertson, N. R. [5 ]
Mahajan, A. [6 ]
Walker, M. [7 ]
Gough, S. [8 ]
Zhou, K. [1 ]
Forgie, I. [1 ]
Ruetten, H. [9 ]
Pavo, I. [10 ]
Pillai, S. G. [10 ]
Jones, A. G. [3 ,4 ]
Pearson, E. R. [1 ]
机构：
[1] Univ Dundee, Mol & Clin Med, Dundee, Scotland
[2] CNR, Inst Neurosci, Padua, Italy
[3] Univ Exeter, NIHR Exeter Clin Res Facil, Exeter, Devon, England
[4] Royal Devon & Exeter Hosp, Exeter, Devon, England
[5] Univ Oxford, Wellcome Trust Ctr Human Genet, Mol & Clin Med, Oxford, England
[6] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England
[7] Newcastle Univ, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, England
[8] NIHR Oxford Biomed Res Ctr, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England
[9] Sanofi Aventis Deutsch GmbH, TMED, Frankfurt, Germany
[10] Eli Lilly Res Labs, Indianapolis, IN USA
来源：
DIABETOLOGIA | 2018年 / 61卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
39
引用
收藏
页码：S21 / S21
页数：1
相关论文
共 50 条
  • [21] Variable Responses to GLP-1 Receptor Agonists
    Kunwar, Sandeep
    Samson, Kaeli
    Davis, Clifton
    Shivaswamy, Vijay
    Desouza, Cyrus
    DIABETES, 2022, 71
  • [22] GLP-1 Receptor Agonists and Kidney Protection
    Greco, Eulalia Valentina
    Russo, Giuseppina
    Giandalia, Annalisa
    Viazzi, Francesca
    Pontremoli, Roberto
    De Cosmo, Salvatore
    MEDICINA-LITHUANIA, 2019, 55 (06):
  • [23] GLP-1 receptor agonists and cardiovascular safety
    Huang, Yu-Yao
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2016, 120 : S20 - S20
  • [24] The Cautious Promise of GLP-1 Receptor Agonists
    Dauterive, Rachel S.
    OCHSNER JOURNAL, 2024, 24 (03): : 165 - 166
  • [25] Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
    Liu, Qiyuan Keith
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [26] The Impact of GLP-1 Receptor Agonists (GLP-1 RAs) on Mental Health: A Systematic Review
    Silvia Tempia Valenta
    Alba Nicastri
    Federica Perazza
    Federica Marcolini
    Valentina Beghelli
    Anna Rita Atti
    Maria Letizia Petroni
    Current Treatment Options in Psychiatry, 2024, 11 (4) : 310 - 357
  • [27] Down regulation of the GLP-1 receptor caused by GLP-1 is associated to increased receptor internalization.
    Brock, B
    Gregersen, S
    Hermansen, K
    DIABETOLOGIA, 1999, 42 : A199 - A199
  • [28] Determinants of glucagon-like peptide-1 (GLP-1) response in prediabetes and diabetes: an IMI-DIRECT study
    Dawed, A. Y.
    Franks, P. W.
    Walker, M.
    Mari, A.
    Pearson, E. R.
    DIABETIC MEDICINE, 2016, 33 : 10 - 10
  • [29] Brain GLP-1 and the regulation of food intake: GLP-1 action in the brain and its implications for GLP-1 receptor agonists in obesity treatment
    Trapp, Stefan
    Brierley, Daniel, I
    BRITISH JOURNAL OF PHARMACOLOGY, 2022, 179 (04) : 557 - 570
  • [30] GLP-1 receptor Gs-cotransfection: A new tool in screening for GLP-1 agonists.
    Knudsen, LB
    Wulff, BS
    DIABETOLOGIA, 1997, 40 : 1459 - 1459
12345