Comparative Analysis of Capsules of Sibutramine Acquired in Formal and Informal Market

"Comparative Analysis of Capsules of Sibutramine Acquired in Formal and Informal Market". Sibutramine is an anorexigenic agent indicated for the treatment of obesity and body weight reduction, together with a food diet and physical exercises. In Brazil, it is found commercially in the pharmaceutical form of 10 and 15 mg capsules. Medication containing this agent can be purchased in Brazil nowadays in both the formal and informal market. Hence, the aim of this study is to do a comparative analysis of uniformity of mass and content between the reference, the generic, the similar, the homeopathic and the informally commercialised medicines, by using spectrophotometry in the ultraviolet region. According to the results obtained, as to the average weight all the samples have fulfilled the specifications; however, in the uniformity of content test only the sample acquired in the informal market presented irregular concentration of the active substance.