Antifungal activity of sterols and triterpenes isolated from Ganoderma annulare

被引：68
|
作者：
Smania, EFA
Delle Monache, F
Smania, A [1 ]
Yunes, RA
Cuneo, RS
机构：
[1] Univ Fed Santa Catarina, Dept Microbiol & Parasitol, BR-88040900 Florianopolis, SC, Brazil
[2] Univ Cattolica Sacro Cuore, Ist Biochim & Biochim Clin, Rome, Italy
[3] Univ Fed Santa Catarina, Dept Quim, BR-88040900 Florianopolis, SC, Brazil
来源：
FITOTERAPIA | 2003年 / 74卷 / 04期
关键词：
Ganoderma annulare; sterols; triterpenes; applanoxidic acids; antifungal activity;
D O I：
10.1016/S0367-326X(03)00064-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Three sterols, 5alpha-ergost-7-en-3beta-ol, 5alpha-ergosta-7,22-dien-3beta-ol and 5,8-epidioxy-5alpha,8alpha-ergosta-6,22-dien-3beta-ol and five triterpenes, applanoxidic acids A, C, F, G and H, have been isolated from Ganoderma annulare. The applanoxidic acids A, C and F were found to inhibit the growth of the fungi Microsporum cannis and Trichophyton mentagrophytes at concentrations of 500 to 1000 mug/ml. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：375 / 377
页数：3
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