Minimax D-optimal designs for the logistic model

被引：50
|
作者：
King, J [1 ]
Wong, WK [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Biostat, Los Angeles, CA 90095 USA
来源：
BIOMETRICS | 2000年 / 56卷 / 04期
关键词：
approximate designs; computer algorithm; D-optimality; efficiency; information matrix; power logistic model;
D O I：
10.1111/j.0006-341X.2000.01263.x
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We propose an algorithm for constructing minimax D-optimal designs for the logistic model when only the ranges of the values for both parameters are assumed known. Properties of these designs are studied and compared with optimal Bayesian designs and Sitter's (1992, Biometrics, 48, 1145-1155) minimax D-optimal kk-designs. Examples of minimax D-optimal designs are presented for the logistic and power logistic models, including a dose-response design for rheumatoid arthritis patients.
引用
收藏
页码：1263 / 1267
页数：5
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