Strategies at the Interface of Drug Discovery and Development: Early Optimization of the Solid State Phase and Preclinical Toxicology Formulation for Potential Drug Candidates

被引：45
|
作者：
Palucki, Michael [1 ]
Higgins, John D. [1 ]
Kwong, Elizabeth [1 ]
Templeton, Allen C. [1 ]
机构：
[1] Merck & Co Inc, Basic Pharmaceut Sci, Merck Res Labs, West Point, PA 19486 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2010年 / 53卷 / 16期
关键词：
DISSOLUTION; SOLUBILITY; SELECTION; BIOAVAILABILITY; ABSORPTION; DELIVERY;
D O I：
10.1021/jm1002638
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：5897 / 5905
页数：9
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