High-resolution frequency-domain second-harmonic optical coherence tomography

被引：16
|
作者：
Su, Jianping [1 ]
Tomov, Ivan V. [1 ]
Jiang, Yi [1 ]
Chen, Zhongping [1 ]
机构：
[1] Univ Calif Irvine, Dept Biomed Engn, Beckman Laser Inst & Med Clin, Irvine, CA 92697 USA
来源：
APPLIED OPTICS | 2007年 / 46卷 / 10期
关键词：
D O I：
10.1364/AO.46.001770
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We used continuum generated in an 8.5 cm long fiber by a femtosecond Yb fiber laser to improve threefold the axial resolution of frequency domain second-harmonic optical coherence tomography (SH-OCT) to 12 mu m. The acquisition time was shortened by more than 2 orders of magnitude compared to the time-domain SH-OCT. The system was applied to image biological tissue of fish scales, pig leg tendon, and rabbit eye sclera. Highly organized collagen fibrils can be visualized in the recorded images. Polarization dependence on the SH has been used to obtain polarization resolved images. (c) 2007 Optical Society of America.
引用
收藏
页码：1770 / 1775
页数：6
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