Multidrug-resistant cytomegalovirus infection in a patient with granulomatosis with polyangiitis during immunosuppressive treatment

被引：0

作者：

Piccirilli, Giulia ^{[1
]}

Chiereghin, Angela ^{[1
]}

Maritati, Martina ^{[2
]}

Turello, Gabriele ^{[1
]}

Felici, Silvia ^{[1
]}

La Corte, Renato ^{[3
]}

Gabrielli, Liliana ^{[1
]}

Contini, Carlo ^{[2
]}

Lazzarotto, Tiziana ^{[1
]}

机构：

[1] Univ Bologna, Dept Specialized Expt & Diagnost Med, Microbiol Unit, Lab Virol,St Orsola Polyclin, Bologna, Italy

[2] Univ Ferrara, Dept Med Sci, Sect Infect Dis & Dermatol, Ferrara, Italy

[3] Univ Ferrara, Dept Med Sci, Sect Hematol & Rheumatol, Ferrara, Italy

来源：

ANTIVIRAL THERAPY | 2020年 / 25卷 / 02期

关键词：

ANTIVIRAL DRUG-RESISTANCE; DISEASES;

D O I：

10.3851/IMP3352

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Cytomegalovirus (CMV) infection is a major complication in immunocompromised patients, including those with autoimmune diseases. Here, we describe the first case of granulomatosis with polyangiitis treated with steroids and cyclophosphamide, complicated by a multidrug-resistant (MDR) CMV infection in presence of weak antiviral cellular immunity. Since reports regarding CMV infection in rheumatological patients are rarely described and no guidelines on its management exist, the described case contributes to identify potential strategies to predict the risk of CMV disease and developing of MDR-CMV in these patients, through virological and immunological surveillance.

引用

页码：111 / 114

页数：4

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