Microbe Profile: Aspergillus fumigatus: a saprotrophic and opportunistic fungal pathogen

被引：26
|
作者：
Fang, Wenxia [1 ]
Latge, Jean-Paul [2 ]
机构：
[1] Guangxi Acad Sci, State Key Lab Nonfood Biomass & Enzyme Technol, Guangxi Key Lab Biorefinery, Natl Engn Res Ctr Nonfood Biorefinery, Nanning, Peoples R China
[2] Inst Pasteur, Unite Aspergillus, Paris, France
来源：
MICROBIOLOGY-SGM | 2018年 / 164卷 / 08期
关键词：
Aspergillus fumigatus; cell wall; Immune response; saprotrophic; polysaccharides;
D O I：
10.1099/mic.0.000651
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Aspergillus fumigatus is a saprotrophic fungus that continuously disseminates spores (conidia) into the environment. It is also the most common and opportunistic aerial fungal pathogen, causing allergic and chronic lung pathologies including the fatal invasive aspergillosis in immunocompromised patients. The pathobiology of aspergillosis is complex and depends on the competence of the host immune system. Moreover, A. fumigatus has become a model to study unique features of fungi. This includes the fungal cell wall, which not only acts as a rigid skeleton for protection against hostile environments but also plays significant roles during infection by manipulating the host immune response.
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页码：1009 / 1011
页数：3
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