Study on the effects of grape seed extract in ehrlich ascitic carcinoma

被引：0
|
作者：
Adriana, Muresan [1 ]
Suciu, Soimita [1 ]
Clichici, Simona [1 ]
Daicoviciu, Doina [1 ]
Pop, Nastasia [2 ]
Potescu, I. D. [3 ]
机构：
[1] Univ Med & Pharm, Cluj Napoca, Romania
[2] Univ Agr Sci & Vet Med, Cluj Napoca, Romania
[3] I Chiricuta Oncol Inst, Cluj Napoca, Romania
来源：
BULLETIN OF THE UNIVERSITY OF AGRICULTURAL SCIENCES AND VETERINARY MEDICINE, VOL 63, 2006: VETERINARY MEDICINE | 2006年 / 63卷
关键词：
oxidative stress; grape seed extract; doxorubicin; Ehrlich ascitic carcinoma;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The seed extract (GSE) of Burgund Mare de Recas grape variety was evaluated for antitumor activity against Ehrlich ascites carcinoma(EAC)-bearing Swiss albino mice. The antioxidant activity of GSE was also estimated in EAC-bearing mice treated with doxorubicin 2x0.1 mg/mouse. The composition in polyphenols of the GSE, expressed as gallic acid, consisted of 11.477mg/l. The anti-tumor activity of GSE was assessed by measuring the tumor volume and by counting the tumor cells. As oxidative stress parameters the total thiobarbituric reactive reactive substances (TBARS) in the plasma were measured. The results indicate that GSE does not dot possess antitumor activity against Ehrlich ascitic carcinoma cells, does not interfere with the antitumor effects of doxorubicin in EAC-bearing mice and decreases the lipid peroxidation induced by doxorubicin treatment. http://journals.usamvcluj.ro/index.php/veterinary/article/view/2438/2416
引用
收藏
页码：114 / +
页数：3
相关论文
共 50 条
  • [1] Effects of Grape Seed Proanthocyanidin Extract on Obesity
    Liu, Miao
    Yun, Peng
    Hu, Ying
    Yang, Jiao
    Khadka, Rim Bahadur
    Peng, Xiaochun
    OBESITY FACTS, 2020, 13 (02) : 279 - 291
  • [2] Inhibitory effects of grape seed extract on lipases
    Moreno, DA
    Ilic, N
    Poulev, A
    Brasaemle, DL
    Fried, SK
    Raskin, I
    NUTRITION, 2003, 19 (10) : 876 - 879
  • [3] Effects of grape seed extract on periodontal disease: an experimental study in rats
    Ozden, Feyza Otan
    Sakallioglu, Elif Eser
    Sakallioglu, Umur
    Ayas, Bulent
    Erisgin, Zuleyha
    JOURNAL OF APPLIED ORAL SCIENCE, 2017, 25 (02) : 121 - 129
  • [4] Effects of Cisplatin on Lymphocyte Structure and Functions in Mice with Ehrlich Ascitic Carcinoma
    Zamay, T. N.
    Kolovskaya, O. S.
    Zamay, G. S.
    Borodina, N. A.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2011, 151 (01) : 62 - 65
  • [5] Effects of Cisplatin on Lymphocyte Structure and Functions in Mice with Ehrlich Ascitic Carcinoma
    T. N. Zamay
    O. S. Kolovskaya
    G. S. Zamay
    N. A. Borodina
    Bulletin of Experimental Biology and Medicine, 2011, 151 : 62 - 65
  • [6] Grape seed extract
    不详
    AGRO FOOD INDUSTRY HI-TECH, 1997, 8 (01): : 52 - 52
  • [7] THE STUDY OF ANTIMICROBIAL EFFECT OF GRAPE SEED EXTRACT
    Rozsova, Ivana
    Sochor, Jiri
    Tomaskova, Lenka
    Baron, Mojmir
    Prusova, Bozena
    Kalhotka, Libor
    Burdova, Eva
    PROCEEDINGS OF INTERNATIONAL PHD STUDENTS CONFERENCE, (MENDELNET 2016), 2016, : 634 - 638
  • [8] Effects of Grape Seed Extract on Diabetic Neuropathy in Mice
    Yurt, Aysegul
    Koksal, Burcu
    Gurbuz, Perihan
    Yildiz, Azibe
    Vardi, Nigar
    Alcin, Ergul
    ACTA PHYSIOLOGICA, 2015, 215 : 51 - 52
  • [9] THE EFFECTS OF GRAPE SEED EXTRACT ON QUALITY CHARACTERISTICS OF FRANKFURTERS
    Ozvural, Emin Burcin
    Vural, Halil
    JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2012, 36 (04) : 291 - 297
  • [10] The effects of a grape seed extract on ligature induced - periodontitis in rats - an experimental study
    Dimitriu, Tudor
    Daradics, Zsofia
    Suciu, Soimita
    Cimpean, Adrian
    Catoi, Cornel
    Armencea, Gabriel
    Baciut, Grigore
    Baciut, Mihaela
    ROMANIAN BIOTECHNOLOGICAL LETTERS, 2021, 26 (01): : 2347 - 2354
12345