Development of proton CT imaging system using plastic scintillator and CCD camera

被引:19
|
作者
Tanaka, Sodai [1 ]
Nishio, Teiji [2 ,3 ]
Matsushita, Keiichiro [2 ]
Tsuneda, Masato [4 ]
Kabuki, Shigeto [5 ]
Uesaka, Mitsuru [6 ]
机构
[1] Univ Tokyo, Sch Engn, Dept Nucl Engn & Management, Bunkyo Ku, 2-11-16 Yayoi, Tokyo 1130032, Japan
[2] Hiroshima Univ, Inst Biomed & Hlth Sci, Dept Radiat Oncol, Minami Ku, 1-2-3 Kasumi, Hiroshima 7348551, Japan
[3] Hiroshima Univ, Org Leading Grad Educ Program, Minami Ku, 1-2-3 Kasumi, Hiroshima 7348551, Japan
[4] Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Radiat Oncol, Minami Ku, 1-2-3 Kasumi, Hiroshima 7348551, Japan
[5] Tokai Univ, Sch Med, Dept Radiat Oncol, 143 Shimokasuya Isehara, Shibuya, Kanagawa 2591193, Japan
[6] Univ Tokyo, Nucl Profess Sch, Sch Engn, Naka Ku, 22-2 Shirane Shirakata, Tokai, Ibaraki 1130032, Japan
来源
PHYSICS IN MEDICINE AND BIOLOGY | 2016年 / 61卷 / 11期
关键词
proton therapy; computed tomography; plastic scintillator plus CCD camera; treatment planning; range verification; COMPUTED-TOMOGRAPHY; CALIBRATION; THERAPY;
D O I
10.1088/0031-9155/61/11/4156
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A proton computed tomography (pCT) imaging system was constructed for evaluation of the error of an x-ray CT (xCT)-to-WEL (water-equivalent length) conversion in treatment planning for proton therapy. In this system, the scintillation light integrated along the beam direction is obtained by photography using the CCD camera, which enables fast and easy data acquisition. The light intensity is converted to the range of the proton beam using a light-to-range conversion table made beforehand, and a pCT image is reconstructed. An experiment for demonstration of the pCT system was performed using a 70 MeV proton beam provided by the AVF930 cyclotron at the National Institute of Radiological Sciences. Three-dimensional pCT images were reconstructed from the experimental data. A thin structure of approximately 1 mm was clearly observed, with spatial resolution of pCT images at the same level as that of xCT images. The pCT images of various substances were reconstructed to evaluate the pixel value of pCT images. The image quality was investigated with regard to deterioration including multiple Coulomb scattering.
引用
收藏
页码:4156 / 4167
页数:12
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