Two new flavanone glycosides from Scutellaria galericulata with anti-inflammatory activities

被引：3

作者：

Xiao, Kai ^{[1
]}

Han, Qing-Tong ^{[1
]}

Zhang, Lei ^{[1
]}

Dai, Sheng-Jun ^{[1
]}

机构：

[1] Yantai Univ, Sch Pharmaceut Sci, Yantai 264005, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2017年 / 20卷

关键词：

Scutellaria galericulata; Labiatae; Flavanone glycoside; Scugalerosides A-B; Anti-inflammatory activity; NEOCLERODANE DITERPENOIDS; ANTICANCER ACTIVITY; MAGNETIC-RESONANCE; PHENOLIC-COMPOUNDS; C-13; NMR; CONFIGURATION;

D O I：

10.1016/j.phytol.2017.04.036

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new flavanone glycosides, named scugalerosides A and B (1-2), were isolated from the whole plant of Scutellaria galericulata. Their chemical structures including absolute configurations were established on the basis of detailed physical data analyses. In vitro, two new compounds showed anti-inflammatory activities, with the inhibition rates of release of beta-glucuronidase from polymorphonuclear leukocytes of rats being 43.7% and 45.1% at concentrations of 10 mu M.

引用

页码：151 / 154

页数：4

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