A novel presentation of Addison disease: Hypoglycemia unawareness in an adolescent with insulin-dependent diabetes mellitus

被引：12
|
作者：
Phornphutkul, C
Boney, CM
Gruppuso, PA
机构：
[1] Rhode Isl Hosp, Dept Pediat, Div Pediat Endocrinol, Providence, RI 02903 USA
[2] Brown Univ, Providence, RI 02912 USA
来源：
JOURNAL OF PEDIATRICS | 1998年 / 132卷 / 05期
关键词：
D O I：
10.1016/S0022-3476(98)70325-7
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
A 16-year-old boy with insulin-dependent diabetes mellitus (IDDM) and a history of marginal glycemic control had severe hypoglycemia unawareness and a marked decrease in insulin requirement. His counterregulatory hormone response at the time of hypoglycemia suggested adrenocortical and adrenomedullary dysfunction. Further testing confirmed Addison disease. The patient's hypoglycemia unawareness was reversed by glucocorticoid replacement, although the plasma epinephrine response to hypoglycemia remained undetectable.
引用
收藏
页码：882 / 884
页数：3
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