Longitudinally tracking fluoroquinolone resistance and its determinants in penicillin-susceptible and -nonsusceptible Streptococcus pneumoniae isolates in Hong Kong, 2000 to 2005

被引：22

作者：

Ip, Margaret ^{[1
]}

Chau, Shirley S. L. ^{[1
]}

Chi, Fang ^{[1
]}

Cheuk, Edmund S. C. ^{[1
]}

Ma, Helen ^{[1
]}

Lai, Raymond W. M. ^{[1
]}

Chan, Paul K. ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 06期

关键词：

D O I：

10.1128/AAC.00139-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Of 1,388 Streptococcus pneumoniae isolates collected from 2000 to 2005, 10.5% had a ciprofloxacin MIC of >= 4.0 mu g/ml and 1.6% (range, 0.8% to 4.3% per year) had a levofloxacin MIC of >= 4.0 mu g/ml. Molecular characterization indicated that fluoroquinolone resistance occurred independently in our prevalent Spain(23F)-1 clone, expressing serotypes 23F, 19F, and 14. Rates of resistance to levofloxacin in S. pneumoniae have remained stable at a Hong Kong hospital.

引用

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页码：2192 / 2194

页数：3

共 44 条

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