Longitudinally tracking fluoroquinolone resistance and its determinants in penicillin-susceptible and -nonsusceptible Streptococcus pneumoniae isolates in Hong Kong, 2000 to 2005

被引:22
|
作者
Ip, Margaret [1 ]
Chau, Shirley S. L. [1 ]
Chi, Fang [1 ]
Cheuk, Edmund S. C. [1 ]
Ma, Helen [1 ]
Lai, Raymond W. M. [1 ]
Chan, Paul K. [1 ]
机构
[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.1128/AAC.00139-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Of 1,388 Streptococcus pneumoniae isolates collected from 2000 to 2005, 10.5% had a ciprofloxacin MIC of >= 4.0 mu g/ml and 1.6% (range, 0.8% to 4.3% per year) had a levofloxacin MIC of >= 4.0 mu g/ml. Molecular characterization indicated that fluoroquinolone resistance occurred independently in our prevalent Spain(23F)-1 clone, expressing serotypes 23F, 19F, and 14. Rates of resistance to levofloxacin in S. pneumoniae have remained stable at a Hong Kong hospital.
引用
收藏
页码:2192 / 2194
页数:3
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