The therapeutic use of quercetin in ophthalmology: recent applications

被引：41
|
作者：
Zhao, Lianghui [1 ,2 ]
Wang, Hongwei [2 ,3 ]
Du, Xianli [2 ,3 ]
机构：
[1] Weifang Med Univ, Weifang 261021, Shandong, Peoples R China
[2] Shandong First Med Univ, Qingdao Eye Hosp, Qingdao 266071, Shandong, Peoples R China
[3] Shandong First Med Univ & Shandong Acad Med Sci, State Key Lab Cultivat Base, Shandong Prov Key Lab Ophthalmol, Shandong Eye Inst, Qingdao 266071, Shandong, Peoples R China
来源：
BIOMEDICINE & PHARMACOTHERAPY | 2021年 / 137卷
关键词：
Therapeutic quercetin; Ophthalmic diseases; Bioactivity; Anti-oxidant; Anti-inflammatory; EPITHELIAL-MESENCHYMAL TRANSITION; ORBITAL FIBROBLASTS; OXIDATIVE STRESS; ALLERGIC CONJUNCTIVITIS; MACULAR DEGENERATION; INSULIN-RESISTANCE; OCULAR SURFACE; IN-VIVO; CELLS; INHIBITION;
D O I：
10.1016/j.biopha.2021.111371
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Quercetin is a natural flavonol antioxidant found in various plant sources and food samples. It is well known for its notable curative effects on the treatment of ophthalmic diseases due to various biological activities, such as antioxidant, anti-inflammatory, and anti-fibrosis activities. This review will discuss the latest developments in therapeutic quercetin for the treatment of keratoconus, Graves? orbitopathy, ocular surface, cataracts, glaucoma, retinoblastoma, and other retinal diseases.
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页数：7
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