Megakaryocytes in the hematopoietic stem cell niche

被引：10
|
作者：
Day, Ryan B. [1 ]
Link, Daniel C. [1 ]
机构：
[1] Washington Univ, Dept Med, St Louis, MO 63130 USA
来源：
NATURE MEDICINE | 2014年 / 20卷 / 11期
关键词：
BONE-MARROW NICHE; MAINTENANCE; QUIESCENCE;
D O I：
10.1038/nm.3745
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Mesenchymal stromal cells are key components of hematopoietic stem cell (HSC) niches in the bone marrow. Two studies now show that hematopoietic-derived megakaryocytes also contribute to the HSC niche, regulating HSC quiescence and function.
引用
收藏
页码：1233 / 1234
页数：2
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