Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer (vol 289, pg 26417, 2014)

被引:3
|
作者
Dalal, Kush
Roshan-Moniri, Mani
Sharma, Aishwariya
Li, Huifang
Ban, Fuqiang
Hessein, Mohamed
Hsing, Michael
Singh, Kriti
LeBlanc, Eric
Dehm, Scott
Tomlinson Guns, Emma S.
Cherkasov, Artem
Rennie, Paul S.
机构
关键词
D O I
10.1074/jbc.A114.553818
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:33877 / 33877
页数:1
相关论文
共 50 条
  • [21] A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells
    Auvin, Serge
    Ozturk, Harun
    Abaci, Yusuf T.
    Mautino, Gisele
    Meyer-Losic, Florence
    Jollivet, Florence
    Bashir, Tarig
    de The, Hugues
    Sahin, Umut
    [J]. LIFE SCIENCE ALLIANCE, 2019, 2 (04)
  • [22] Identification of a highly conserved domain in the androgen receptor that suppresses the DNA-binding domain-DNA interactions
    Liu, GZ
    Wang, H
    Wang, ZX
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (17) : 14956 - 14960
  • [23] De Novo Design of an Androgen Receptor DNA Binding Domain-Targeted peptide PROTAC for Prostate Cancer Therapy
    Ma, Bohan
    Fan, Yizeng
    Zhang, Dize
    Wei, Yi
    Jian, Yanlin
    Liu, Donghua
    Wang, Zixi
    Gao, Yang
    Ma, Jian
    Chen, Yule
    Xu, Shan
    Li, Lei
    [J]. ADVANCED SCIENCE, 2022, 9 (28)
  • [24] BACKBONE DYNAMICS OF THE GLUCOCORTICOID RECEPTOR DNA-BINDING DOMAIN (VOL 31, PG 12001, 1992)
    BERGLUND, H
    KOVACS, H
    DAHLMANWRIGHT, K
    GUSTAFSSON, JA
    HARD, T
    [J]. BIOCHEMISTRY, 1993, 32 (14) : 3829 - 3829
  • [25] Inhibitors of the transactivation domain of androgen receptor as a therapy for prostate cancer
    Obst, Jon K.
    Tien, Amy H.
    Setiawan, Josie C.
    Deneault, Lauren F.
    Sadar, Marianne D.
    [J]. STEROIDS, 2024, 210
  • [26] DNA-binding domain as an alternative target site on androgen receptor for prostate cancer therapy: Pre-clinical in vivo study of a novel small molecule for drug development
    Hassona, Mohamed D. H.
    Chan, Leslie G.
    Meckling, Gray R.
    Li, Huifang
    LeBlanc, Eric
    Ban, Fuqiang
    Cherkasov, Artem
    Rennie, Paul S.
    Guns, Emma
    [J]. CANCER RESEARCH, 2015, 75
  • [28] Complete Androgen Insensitivity Syndrome due to Mutations in the DNA-Binding Domain of the Human Androgen Receptor Gene
    Chauhan, Pooja
    Rani, Anjali
    Singh, Surya K.
    Rai, Amit K.
    [J]. SEXUAL DEVELOPMENT, 2018, 12 (06) : 269 - 274
  • [29] Response to treatment in patients with partial androgen insensitivity due to mutations in the DNA-binding domain of the androgen receptor
    Giwercman, YL
    Nikoshkov, A
    Lindsten, K
    Byström, B
    Pousette, Å
    Knudtzon, J
    Alm, J
    Wedell, A
    [J]. HORMONE RESEARCH, 2000, 53 (02) : 83 - 88
  • [30] POINT MUTATION IN THE DNA-BINDING DOMAIN OF THE ANDROGEN RECEPTOR IN 2 FAMILIES WITH REIFENSTEIN SYNDROME
    KLOCKER, H
    KASPAR, F
    EBERLE, J
    UBERREITER, S
    RADMAYR, C
    BARTSH, G
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1992, 50 (06) : 1318 - 1327