A Bayesian stochastic SIRS model with a vaccination strategy for the analysis of respiratory syncytial virus

被引:10
|
作者
Jornet-Sanz, M. [1 ]
Corberan-Vallet, A. [1 ]
Santonja, F. J. [1 ]
Villanueva, R. J. [2 ]
机构
[1] Univ Valencia, Dept Stat & Operat Research, Fac Mathematics, Dr Moliner 50, E-46100 Burjassot, Spain
[2] Univ Politecn Valencia, Inst Multidisciplinary Math, Bldg 8G,2 Floor,Camino Vera S-N, E-46022 Valencia, Spain
关键词
Infectious diseases; respiratory syncytial virus (RSV); discrete-time epidemic model; stochastic compartmental model; Bayesian analysis; intervention strategies; EPIDEMIC MODELS; RSV; TRANSMISSION; PARAMETERS; INFERENCE; INFLUENZA; DYNAMICS; DISEASE;
D O I
10.2436/20.8080.02.56
中图分类号
C93 [管理学]; O22 [运筹学];
学科分类号
070105 ; 12 ; 1201 ; 1202 ; 120202 ;
摘要
Our objective in this paper is to model the dynamics of respiratory syncytial virus in the region of Valencia (Spain) and analyse the effect of vaccination strategies from a health-economic point of view. Compartmental mathematical models based on differential equations are commonly used in epidemiology to both understand the underlying mechanisms that influence disease transmission and analyse the impact of vaccination programs. However, a recently proposed Bayesian stochastic susceptible-infected-recovered-susceptible model in discrete-time provided an improved and more natural description of disease dynamics. In this work, we propose an extension of that stochastic model that allows us to simulate and assess the effect of a vaccination strategy that consists on vaccinating a proportion of newborns.
引用
收藏
页码:159 / 175
页数:17
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