A Promising New Family of Peptide-Modified AAV Capsids for Gene Delivery to the Central Nervous System in Non-Human Primates

被引:0
|
作者
Chan, Ken Y. [1 ]
Pacouret, Simon [1 ]
Huang, Qin [1 ]
Zheng, Qingxia [1 ]
Vandenburg, Charles [1 ]
Wu, Jason [1 ]
Brauer, Pamela [1 ]
Zhang, Qiangge [2 ]
Tobey, Isabelle [1 ]
Wu, Carolyn [2 ]
Chen, Albert T. [1 ]
Kozareva, Velina [1 ]
Feng, Guoping [1 ,2 ]
Deverman, Benjamin E. [1 ]
机构
[1] Broad Inst MIT & Harvard, Stanley Ctr Psychiat Res, Cambridge, MA 02142 USA
[2] MIT, McGovern Inst Brain Res, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
1197
引用
收藏
页码:556 / 556
页数:1
相关论文
共 50 条
  • [21] Optimization of intrathecal delivery of an infused AAV9 vector for delivery of a gene therapy candidate for adrenomyeloneuropathy in non-human primates
    Vasireddy, V.
    Clark, S. W.
    Anderson, D. W.
    Kozarsky, K.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A27 - A27
  • [22] The carcinoembryonic antigen (CEA) gene family in non-human primates
    Zhou, GQ
    Zhang, Y
    Hammarström, S
    GENE, 2001, 264 (01) : 105 - 112
  • [23] Erratum: Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates
    S J Gray
    S Nagabhushan Kalburgi
    T J McCown
    R Jude Samulski
    Gene Therapy, 2013, 20 (4) : 465 - 465
  • [24] The type 2 cystatin gene family of non-human primates
    Haga, T
    Minaguchi, K
    Takenaka, O
    JOURNAL OF DENTAL RESEARCH, 1996, 75 : 1463 - 1463
  • [25] Recombinant AAV-mediated gene delivery to the central nervous system
    Tenenbaum, L
    Chtarto, A
    Lehtonen, E
    Velu, T
    Brotchi, J
    Levivier, M
    JOURNAL OF GENE MEDICINE, 2004, 6 : S212 - S222
  • [26] Gene Delivery to Non-Human Primate Embryos Using AAV Vectors
    Wang, Dan
    Niu, Yuyu
    Ren, Lingzhi
    Tai, Phillip W. L.
    Ji, Weizhi
    Gao, Guangping
    MOLECULAR THERAPY, 2019, 27 (04) : 110 - 110
  • [27] A comprehensive study of a 29-capsid AAV library in a non-human primate central nervous system
    Kondratov, Oleksandr
    Kondratova, Liudmyla
    Mandel, Ronald J.
    Coleman, Kirsten
    Savage, Michael A.
    Gray-Edwards, Heather L.
    Ness, Timothy J.
    Rodriguez-Lebron, Edgar
    Bell, Robert D.
    Rabinowitz, Joseph
    Gamlin, Paul D.
    Zolotukhin, Sergei
    MOLECULAR THERAPY, 2021, 29 (09) : 2806 - 2820
  • [28] Successful Repeated Hepatic Gene Delivery in Non-Human Primates Achieved with AAV5 by Use of Immune Adsorption
    Salas, David
    Kwikkers, Karin
    Majowicz, Anna
    Zabaleta, Nerea
    Petry, Harald
    Gonzalez Aseguinolaza, Gloria
    Ferreira, Valerie
    MOLECULAR THERAPY, 2017, 25 (05) : 183 - 183
  • [29] Immune-driven gene expression loss following intramuscular AAV delivery to non-human primates is only transient
    Journou, Malo
    Devaux, Marie
    Jaulin, Nicolas
    Pichard, Virginie
    Segovia, Mercedes
    Moreau, Aurelie
    Le Duff, Johanne
    Cuturi, Maria Cristina
    Guilbaud, Mickael
    Adjali, Oumeya
    MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2025, 33 (01)
  • [30] Successful repeated hepatic gene delivery in non-human primates achieved with AAV5 by use of immune adsorption
    Salas, D.
    Kwikkers, K.
    Majowicz, A.
    Zabaleta, N.
    Petry, H.
    Ferreira, V.
    Gonzalez-Aseguinolaza, G.
    HUMAN GENE THERAPY, 2017, 28 (12) : A102 - A103