PRDM9 points the zinc finger at meiotic recombination hotspots

被引：18
|
作者：
Neale, Matthew J. [1 ]
机构：
[1] Univ Sussex, MRC, Genome Damage & Stabil Ctr, Brighton BN1 9RQ, E Sussex, England
来源：
GENOME BIOLOGY | 2010年 / 11卷 / 02期
基金：
英国医学研究理事会;
关键词：
INITIATION;
D O I：
10.1186/gb-2010-11-2-104
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Meiotic recombination events are spread nonrandomly across eukaryotic genomes in 'hotspots'. Recent work shows that a unique histone methyltransferase, PRDM9, determines their distribution.
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收藏
页数：3
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