Mediastinal polyembryoma associated with Klinefelter syndrome

被引:14
|
作者
Beresford, L
Fernandez, CV
Cummings, E
Sanderson, S
Min-Yu, W
Giacomantonio, M
机构
[1] Mem Univ Newfoundland, Dept Pediat, St Johns, NF A1C 5S7, Canada
[2] Dalhousie Univ, Dept Pediat, Halifax, NS, Canada
[3] Dalhousie Univ, Dept Pathol, Halifax, NS, Canada
[4] Dalhousie Univ, Dept Surg, Halifax, NS B3H 4H2, Canada
关键词
germ cell tumor; Klinefelter; polyembryoma; precocious puberty;
D O I
10.1097/00043426-200304000-00011
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection dernonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. On further investigation he vas found to have Klinefelter syndrome. Most mediastinal germ Cell tumors are treated with adjuvant therapy. He was managed with surgical excision alone and is well at 2 years follow-up. The rationale for this approach is discussed.
引用
收藏
页码:321 / 323
页数:3
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