Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies

被引：228

作者：

Rojas, I

Graus, F

Keime-Guibert, F

Reñé, R

Delattre, JY

Ramón, JM

Dalmau, J

Posner, JB

机构：

[1] Univ Barcelona, Hosp Clin Barcelona, Serv Neurol, E-08036 Barcelona, Spain

[2] Univ Barcelona, Hosp Clin Barcelona, Inst Invest Biomed August Pi & Sunyer, E-08036 Barcelona, Spain

[3] Ciudad Sanitaria & Univ Bellvitge, Serv Neurol, Hospitalet, Spain

[4] Ciudad Sanitaria & Univ Bellvitge, Serv Prevent Med, Hospitalet, Spain

[5] Hop La Pitie Salpetriere, Serv Neurol, Paris, France

[6] Mem Sloan Kettering Canc Ctr, Dept Neurol, New York, NY 10021 USA

来源：

NEUROLOGY | 2000年 / 55卷 / 05期

关键词：

D O I：

10.1212/WNL.55.5.713

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The outcome of 34 women with anti-Yo-associated paraneoplastic cerebellar degeneration was reviewed. Three patients had not developed cancer after more than 4 years of follow-up. The only independent predictor for survival was the type of associated tumor (risk ratio, 1.79; 95% CI, 1.02 to 3.12). Median survival was 100 months for patients with breast cancer sind 22 for those with gynecologic cancer. Although paraneoplastic cerebellar degeneration leads to the diagnosis of cancer in 63% of the patients, cancer progression was the cause of death in 52%.

引用

页码：713 / 715

页数：3

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