New oral anticoagulant drugs mechanisms of action

被引：0
|
作者：
Brighton, Timothy [1 ,2 ]
机构：
[1] S Eastern Area Lab Serv, Sydney, NSW, Australia
[2] Prince Wales Hosp, Sydney, NSW, Australia
来源：
AUSTRALIAN PRESCRIBER | 2010年 / 33卷 / 02期
关键词：
dabigatran etexilate; rivaroxaban; INHIBITOR;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In 2008, two new oral anticoagulant drugs were registered in Australia for the prevention of venous thrombosis after elective knee or hip replacement. Rivaroxaban is a direct reversible competitive antagonist of activated factor X. Dabigatran etexilate is a direct reversible competitive antagonist of thrombin. Both drugs are effective anticoagulants which offer potential advantages over heparin and warfarin.
引用
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页码：38 / 41
页数：4
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