ONE-POT SYNTHESIS OF FUROFLAVANONES

被引:0
|
作者
Soman, Shubhangi S. [1 ]
Patel, Jagdish M. [1 ]
机构
[1] Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Baroda 390002, Gujarat, India
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Several new furoflavanones (5-7) have been synthesized from hydroxy acetyl benzofuran and an aryl aldehyde in presence of piperidine. These furoflavanones were dehydrogenated to furoflavones (8-10) using DDQ (2,3-dichloro-5,6-dicyano-1,4-benzoquinone). The chalcone synthesized (4b) using 1% ethanolic sodium hydroxide from hydroxy acetyl benzofuran and aryl aldehyde shows promising antiinflammatory activity.
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页码:209 / 214
页数:6
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